Potency specification

15:46 May 22, 2023
English to French translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: Potency specification
Bonjour,
Un exemple tiré du net en guise de contexte.
J’ai ma petite idée, mais c’est toujours plus prudent de vérifier.

The minimum potency specification is usually set based on challenge dose titration studies and the maximum potency on adverse reactions obtained in specific ..
Dr Malick Mbengue
Senegal
Local time: 09:09


Summary of answers provided
4spécification de la dose
Lionel-N
3 -1La dose minimale
Abdelhalim MEKBEL
Summary of reference entries provided
A definition to start with?
Daryo

  

Answers


28 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
potency specification
spécification de la dose


Explanation:
La dose minimale est "extraite" des études dose/réponse (titrage de dose), alors que la dose maximale est basée sur l'insrgence d'EI.
En fait "potency" est assez impropre ici, mais parfois utilisé pour définir la "concentration" du médicament à utiliser (ex, comprimés de 25mg, de 50 mg, de 100 mg......)
Selon le contexte on pourrait peut-être parler de "schéma posologique"

Lionel-N
Italy
Local time: 11:09
Specializes in field
Native speaker of: Native in FrenchFrench
PRO pts in category: 281
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3 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): -1
La dose minimale


Explanation:
La dose minimale dont on a besoin ( généralement en milligrammes) pour produire un effet.

Example sentence(s):
  • Il a besoin de 500 mg minimum du médicament x pour avoir un résultat

    Reference: http://https://www.msdmanuals.com/home/drugs/drug-dynamics/d...
Abdelhalim MEKBEL
Algeria
Local time: 10:09
Works in field
Native speaker of: Native in KabyleKabyle

Peer comments on this answer (and responses from the answerer)
disagree  Lionel-N: la demande n'est pas "minimum potency specification", mais "potency specification"
13 hrs
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Reference comments


1 hr peer agreement (net): +1
Reference: A definition to start with?

Reference information:
Potency (expressed in units):

- quantitative measure of biological activity based on the attribute of the product which is linked to the relevant biological properties, whereas, quantity (expressed in mass) is a physicochemical measure of protein content.

- The results of biological assays should be expressed in units of activity calibrated against an international or national reference standard, when available and appropriate for the assay utilized.

- Where no such reference standard exists, a characterized inhouse reference material should be established and assay results of production lots reported as in-house units.

https://www.ema.europa.eu/en/documents/presentation/presenta...

Daryo
United Kingdom
Native speaker of: Native in SerbianSerbian, Native in FrenchFrench
PRO pts in category: 20

Peer comments on this reference comment (and responses from the reference poster)
agree  Tony M
3 hrs
  -> Thanks!
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