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disulfide self-immolative linker

French translation: lien auto-immolable contenant des ponts disulfure

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:disulfide self-immolative linker
French translation:lien auto-immolable contenant des ponts disulfure
Entered by: Drmanu49

16:43 Jul 7, 2021
English to French translations [PRO]
Tech/Engineering - Biology (-tech,-chem,micro-) / brevet mab
English term or phrase: disulfide self-immolative linker
The present disclosure provides drug-ligand conjugates that are potent cytotoxins, wherein the drug is linked to the ligand through either a peptidyl, hydrazine or disulfide self-immolative linker.
orgogozo
France
Local time: 11:11
espaceur ou lien auto-immolable contenant des ponts disulfure
Explanation:
Étude de systèmes moléculaires programmés - Université de ...
http://theses.univ-poitiers.fr › 2014-Barat-Romain...
PDF
6 févr. 2014 — disulfure, les rotaxanes disposent d'un point d'ancrage pour pouvoir recouvrir ... Un espaceur auto-immolable qui assure la reconnaissance du ...

(PDF) Conjugation of Doxorubicin to siRNA Through Disulfide ...
https://www.researchgate.net › 3422...
· Traduire cette page
16 févr. 2021 — Disulfide-based Self-immolative Linkers ... Two different spacer precursors containing two disulfide bonds ... RNAs were synthesized on an automated DNA synthesizer using standard solid-phase ... une drogue anticancéreuse, la doxorubicine, via un lien auto-immolable contenant des ponts disulfures.
Selected response from:

Drmanu49
France
Local time: 11:11
Grading comment
Merci à tous
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1lieur auto-immolable basé sur des ponts disulfures
Lionel-N
3 +1espaceur ou lien auto-immolable contenant des ponts disulfure
Drmanu49
3un espaceur auto-immolable basé sur des ponts disulfures
Nicolas Gambardella


  

Answers


6 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
espaceur ou lien auto-immolable contenant des ponts disulfure


Explanation:
Étude de systèmes moléculaires programmés - Université de ...
http://theses.univ-poitiers.fr › 2014-Barat-Romain...
PDF
6 févr. 2014 — disulfure, les rotaxanes disposent d'un point d'ancrage pour pouvoir recouvrir ... Un espaceur auto-immolable qui assure la reconnaissance du ...

(PDF) Conjugation of Doxorubicin to siRNA Through Disulfide ...
https://www.researchgate.net › 3422...
· Traduire cette page
16 févr. 2021 — Disulfide-based Self-immolative Linkers ... Two different spacer precursors containing two disulfide bonds ... RNAs were synthesized on an automated DNA synthesizer using standard solid-phase ... une drogue anticancéreuse, la doxorubicine, via un lien auto-immolable contenant des ponts disulfures.

Drmanu49
France
Local time: 11:11
Works in field
Native speaker of: Native in EnglishEnglish, Native in FrenchFrench
PRO pts in category: 538
Grading comment
Merci à tous

Peer comments on this answer (and responses from the answerer)
agree  Samuel Clarisse
4 hrs
  -> Thank you.
neutral  Lionel-N: linker = espaceur ? et spacer c'est quoi alors ?
21 hrs
Login to enter a peer comment (or grade)

36 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
un espaceur auto-immolable basé sur des ponts disulfures


Explanation:
", des liaisons peptiques, ou des hydrazines"

Je pense que l'on parle d'alternatives ici (XOR). La solution de Drmanu49 fonctionne si l'on construit une phrase plus complexe avec "sois ... sois"

Nicolas Gambardella
United Kingdom
Local time: 10:11
Specializes in field
Native speaker of: Native in FrenchFrench
PRO pts in category: 16

Peer comments on this answer (and responses from the answerer)
neutral  Lionel-N: linker = espaceur ? et spacer c'est quoi alors ?
21 hrs
Login to enter a peer comment (or grade)

21 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
lieur auto-immolable basé sur des ponts disulfures


Explanation:
IMHO

Lionel-N
Italy
Local time: 11:11
Specializes in field
Native speaker of: Native in FrenchFrench
PRO pts in category: 236

Peer comments on this answer (and responses from the answerer)
agree  Bertrand Leduc
1 day 20 hrs
  -> Merci Bertrand
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