Glossary entry

English term or phrase:

MGMT unmenthylated

Arabic translation:

محفز الحمض النووي غير المثيلي

Added to glossary by Marwa Seleem
May 1, 2021 11:51
3 yrs ago
15 viewers *
English term

MGMT unmenthylated

English to Arabic Medical Medical: Health Care
Initial diagnosis of glioblastoma multiform in 2018 that is post resection and adjuvant temozolomide based chemoradiotherapy



IDH wild-type, EGFR not amplified, MGMT unmenthylated
Change log

May 7, 2021 22:28: Marwa Seleem Created KOG entry

Proposed translations

+1
45 mins
Selected

محفز الحمض النووي غير المثيلي

MGMT 0 هو جين إصلاح الحمض النووي
https://ar.ovalengineering.com/promoter-hypermethylation-mgm...
وهو اختصار لهذا المصطلح:

unmethylated O 6 -methylguanine-DNA methyltransferase (MGMT),
https://pubmed.ncbi.nlm.nih.gov/25394859/
Peer comment(s):

agree Z-Translations Translator
16 mins
Thank you!
neutral Milena Atanasova : ovalengineering looks like machine translation to me - not only in Arabic.
2 hrs
Thank you for your comment, but by commnsense, it can't be a machine translation, and it is the more accurate translation from a medical point of view!
Something went wrong...
4 KudoZ points awarded for this answer.
23 mins
English term (edited): MGMT unmethylated

ورم أرومي دبقي متعدد الأشكال غير مثيلي

https://ar.wikipedia.org/wiki/ورم_أرومي_دبقي_متعدد_الأشكال
https://ar.wikipedia.org/wiki/مثيلة


--------------------------------------------------
Note added at 27 mins (2021-05-01 12:19:10 GMT)
--------------------------------------------------

unmethylated غير ممثيلي

--------------------------------------------------
Note added at 1 hr (2021-05-01 13:00:48 GMT)
--------------------------------------------------

المحفز الغير مثيلي يقاوم دواء التيموزولوميد في السرطان الأرومي الدبقي متعدد الأشكال
Something went wrong...
8 hrs
English term (edited): MGMT unmethylated

إنزيم ترميم/إصلاح الحمض النووي (MGMT) غير الممثيل

"إنزيم إصلاح الحمض النووي"
https://ara.acousticbiotech.com/enhancing-cytotoxicity-chemo...
"يرتبط مثيل المروج لإنزيم إصلاح الحمض النووي"
https://ara.bioconus.com/mgmt-gene-promoter-methylation-corr...
https://www.biorxiv.org/content/10.1101/317636v1.full

"O6-Methylguanine-DNA Methyltransferase (MGMT) is a DNA repair enzyme that removes alkyl adducts from the O6 position of guanine."

" تحديدا إلى الحمض النووي الممثيل لتجنيد إنزيم..."
" لتضخيم الحمض النووي الممثيل"
"بالإضافة إلى ذلك، يتجمّع إنزيم Parp1 (poly(ADP)-ribose polymerase) مع المركّب ... الاختلافات في الحمض النوويّ الممثيل (الأدينين بدل السيتوسين) مثيلة الأدينين"
"يبدأ إنزيم بوليميراز الدنا Taq-Polymerase بالعمل وتضخيم المنطقة بين ... على إضافة إنزيمات (تميز بين DNA المُمَثيل وغير الممثيل) إلى DNA، تعمل الإنزيمات على ...
"
http://scla.org.sy/magazine/issues/6_2/400.html
https://www.marefa.org/علم_التخلق
https://arabicedition.nature.com/journal/2014/03/nature12931...

Something went wrong...
+1
2 hrs
English term (edited): MGMT unmethylated

ناقِلة مِثيل غوانين مِثيل غير مُمَثيَلة

There is a typographical error in the term "unmenthylated", it should be written "unmethylated", see this link:
https://pubmed.ncbi.nlm.nih.gov/25394859/

According to The Unified Medical Dictionary https://umd.emro.who.int/whodictionary, the word "methylated" means مُمَثيَل, "unmethylated" is the opposite, that is to say: غير مُمَثيَل.

In medicine, MGMT represents an acronym of "Methyl Guanine Methyl Transferase", see here:
https://acronyms.thefreedictionary.com/MGMT

Transferase means ناقلة according to the same medical dictionary mentioned above.

Hence, MGMT can be translated as ناقلة مثيل غوانين مثيل, and the whole expression: ناقِلة مِثيل غوانين مِثيل غير مُمَثيَلة.




--------------------------------------------------
Note added at 4 hrs (2021-05-01 16:16:28 GMT)
--------------------------------------------------

https://ar.m.wikipedia.org/wiki/ناقلة_الميثيل

--------------------------------------------------
Note added at 15 hrs (2021-05-02 02:59:02 GMT)
--------------------------------------------------




--------------------------------------------------
Note added at 15 hrs (2021-05-02 03:05:34 GMT)
--------------------------------------------------


http://www.alqamoos.org/?search_fulltext=Methyltransferase &...
Peer comment(s):

agree Milena Atanasova
8 mins
Thanks
Something went wrong...

Reference comments

2 hrs
Reference:

Peer comments on this reference comment:

agree Lamine Boukabour : Thanks Milena!
4 mins
:) Thank you!
Something went wrong...
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search