Glossary entry

English term or phrase:

allostery

Swedish translation:

allosteri

Mar 9, 2009 19:25
15 yrs ago
English term

allostery

GBK English to Swedish Science Biology (-tech,-chem,micro-)
Definition from Biochemical Society:
Property of some proteins by which spatially separate functional sites in the molecule can communicate with each other via movements transmitted through the structure.
Example sentences:
Oligomerization enables cooperativity between multiple binding sites, a property referred to as allostery or allosteric regulation of enzymes (yet again, single polypeptide, multi-domain proteins show allosteric behavior). (whatislife.com)
The sequential model of allostery holds that subunits are not connected in such a way that a conformational change in one induces a similar change in the others. Thus all enzyme subunits need not exist in the same conformation. (bio-medicine.org)
It also follows that allostery is common and that homologous proteins can have different allosteric mechanisms. (nature.com)
Change log

Mar 9, 2009 16:11: changed "Kudoz queue" from "In queue" to "Public"

Mar 9, 2009 19:25: Mauricio Zoch changed "Stage" from "Preparation" to "Submission"

Mar 12, 2009 19:54: changed "Stage" from "Submission" to "Selection"

Apr 28, 2009 15:54: changed "Stage" from "Selection" to "Completion"

Discussion

Nils Andersson Mar 9, 2009:
allosteri Lots of Google hits on "Swedish pages" about 500.

See e.g. http://xray.bmc.uu.se/Courses/Bke2/OldExams/SampleExamQuesti...

question 17 i.

Nils

Proposed translations

+2
32 mins
Selected

allosteri

Definition from Nationalencyklopedin:
&quot;reglering av enzymaktivitet genom att en liten molekyl (en allosterisk effektor eller allosterisk regulator) binds till ett allosteriskt centrum, som är ett annat ställe på enzymmolekylen än det katalytiska centrumet. Allosteriska effektorer kan vara inhibitorer eller aktivatorer, dvs. ha en hämmande eller stimulerande inverkan på enzymets aktivitet. &quot;<br /><br />Eget tillägg: NE:s definition är egentligen lite för snäv, eftersom det inte behöver röra sig om ett enzym utan kan vara ett annat biologiskt aktivt ämne. Ett klassiskt exempel är hemoglobin, där de fyra subenheternas påverkar varandras syreaffinitet genom en allaosteriks mekanism.
Example sentences:
Ett bra exempel på ett allosteriskt protein är hemoglobin. (Lunds universitet)
Peer comment(s):

agree Anna Klotz
3 days 11 hrs
agree Angelica Kjellström
49 days
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4 KudoZ points awarded for this answer.
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